Early Bactericidal Activity of Meropenem plus Clavulanate (with or without Rifampin) for Tuberculosis: The COMRADE Randomized, Phase 2A Clinical Trial

Author:

De Jager Veronique1ORCID,Gupte Nikhil23,Nunes Silvia1,Barnes Grace L.2,van Wijk Rob Christiaan4ORCID,Mostert Joni1,Dorman Susan E.5,Abulfathi Ahmed A.67,Upton Caryn M.1,Faraj Alan4,Nuermberger Eric L.2,Lamichhane Gyanu2,Svensson Elin M.89ORCID,Simonsson Ulrika S. H.4ORCID,Diacon Andreas H.1,Dooley Kelly E.2ORCID

Affiliation:

1. TASK Applied Science, Cape Town, South Africa;

2. Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland;

3. Johns Hopkins India, Pune, India;

4. Department of Pharmaceutical Biosciences and

5. Medical University of South Carolina, Charleston, South Carolina;

6. Department of Medicine, Stellenbosch University, Cape Town, South Africa;

7. Department of Clinical Pharmacology and Therapeutics, University of Maiduguri, Maiduguri, Nigeria; and

8. Department of Pharmacy, Uppsala University, Uppsala, Sweden;

9. Department of Pharmacy, Radboud University, Njimegen, the Netherlands

Funder

Vetenskapsrådet

National Institute of Allergy and Infectious Diseases

U.S. Food and Drug Administration

Swedish National Infrastructure for Computing

Publisher

American Thoracic Society

Subject

Critical Care and Intensive Care Medicine,Pulmonary and Respiratory Medicine

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