Mucus Plugs and Emphysema in the Pathophysiology of Airflow Obstruction and Hypoxemia in Smokers

Author:

Dunican Eleanor M.1ORCID,Elicker Brett M.2,Henry Travis2,Gierada David S.3,Schiebler Mark L.45,Anderson Wayne6,Barjaktarevic Igor7,Barr R. Graham8,Bleecker Eugene R.9,Boucher Richard C.10,Bowler Russell11,Christenson Stephanie A.612,Comellas Alejandro13ORCID,Cooper Christopher B.7,Couper David14,Criner Gerard J.15,Dransfield Mark16,Doerschuk Claire M.10,Drummond M. Bradley6ORCID,Hansel Nadia N.17,Han MeiLan K.18,Hastie Annette T.19ORCID,Hoffman Eric A.202122,Krishnan Jerry A.23ORCID,Lazarus Stephen C.612,Martinez Fernando J.24,McCulloch Charles E.25,O’Neal Wanda K.10,Ortega Victor E.19,Paine Robert2627,Peters Stephen19,Schroeder Joyce D.28,Woodruff Prescott G.612,Fahy John V.612

Affiliation:

1. Education and Research Centre, St. Vincent’s University Hospital, School of Medicine, University College Dublin, Dublin, Ireland

2. Department of Radiology and Biomedical Imaging

3. Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Missouri

4. Department of Medical Physics and

5. Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin

6. Division of Pulmonary and Critical Care Medicine, Department of Medicine

7. Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of California Los Angeles, Los Angeles, California

8. Division of General Medicine, Department of Medicine, Columbia University, New York City, New York

9. Division of Genetics, Genomics, and Precision Medicine, Department of Medicine, University of Arizona, Tucson, Arizona

10. Marsico Lung Institute/UNC Cystic Fibrosis Center, and

11. Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, National Jewish Health, Denver, Colorado

12. Cardiovascular Research Institute, and

13. Division of Pulmonary, Critical Care, and Occupational Medicine, Department of Internal Medicine

14. Collaborative Studies Coordinating Center, Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina

15. Department of Thoracic Medicine and Surgery, Temple University, Philadelphia, Pennsylvania

16. Division of Pulmonary, Allergy, & Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama

17. Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland

18. Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Michigan at Ann Arbor, Ann Arbor, Michigan

19. Pulmonary, Critical Care, Allergy, and Immunologic Medicine, Department of Internal Medicine, Wake Forest University, Winston-Salem, North Carolina

20. Department of Radiology

21. Department of Medicine, and

22. Department of Biomedical Engineering, University of Iowa, Iowa City, Iowa

23. Division of Pulmonary, Critical Care, Sleep, and Allergy, Department of Medicine, University of Illinois at Chicago, Chicago, Illinois

24. Division of Pulmonary and Critical Care Medicine, Weill Cornell Medicine and New York-Presbyterian Weill Cornell Medical Center, New York, New York

25. Department of Epidemiology and Biostatistics, School of Medicine, University of California San Francisco, San Francisco, California

26. Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Utah Hospitals and Clinics, Salt Lake City, Utah

27. Department of Veterans Affairs Medical Center, Salt Lake City, Utah; and

28. Department of Radiology, University of Utah School of Medicine, Salt Lake City, Utah

Publisher

American Thoracic Society

Subject

Critical Care and Intensive Care Medicine,Pulmonary and Respiratory Medicine

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