Conservative versus Liberal Oxygenation Targets in Intensive Care Unit Patients (ICONIC): A Randomized Clinical Trial

Author:

van der Wal L. Imeen12ORCID,Grim Chloe C. A.12ORCID,del Prado Michael R.1,van Westerloo David J.1ORCID,Boerma E. Christiaan34ORCID,Rijnhart-de Jong Hilda G.4,Reidinga Auke C.5ORCID,Loef Bert G.5ORCID,van der Heiden Pim L. J.6ORCID,Sigtermans Marnix J.7,Paulus Frederique8ORCID,Cornet Alexander D.9ORCID,Loconte Maurizio10,Schoonderbeek F. Jeannette11ORCID,de Keizer Nicolette F.12ORCID,Bakhshi-Raiez Ferishta12ORCID,Le Cessie Saskia13ORCID,Serpa Neto Ary141516ORCID,Pelosi Paolo1017ORCID,Schultz Marcus J.81819ORCID,Helmerhorst Hendrik J. F.2ORCID,de Jonge Evert1ORCID,Wigbers Jeanette,Termorshuizen Fabian,Klop Cintha,Dawson Lilian,Schriel-van den Berg Yvonne,de Vreede Els,Qualm Jolanda,Koopmans Matty,Krol Tim,Rinket Martin,Vermeijden Wytze,Beishuizen Albertus,van Holten Jantine,Tsonas Anissa,Botta Michela,Winters Tineke,Horn Janneke,Battaglini Denise,Ball Lorenzo,Brunetti Iole

Affiliation:

1. Department of Intensive Care,

2. Department of Anesthesiology, and

3. Department of Sustainable Health, Campus Fryslân, University of Groningen, Groningen, The Netherlands;

4. Department of Intensive Care, Medical Center Leeuwarden, Leeuwarden, The Netherlands;

5. Department of Intensive Care, Martini Hospital, Groningen, The Netherlands;

6. Department of Intensive Care, Reinier de Graaf Hospital, Delft, The Netherlands;

7. Department of Intensive Care, Diakonessenhuis, Utrecht, The Netherlands;

8. Department of Intensive Care and

9. Department of Intensive Care, Medisch Spectrum Twente, Enschede, The Netherlands;

10. Department of Anesthesiology and Intensive Care and

11. Department of Intensive Care, Ikazia Hospital, Rotterdam, The Netherlands;

12. Department of Medical Informatics, Amsterdam Public Health – Digital Health, Amsterdam University Medical Center, Location AMC, Amsterdam, The Netherlands;

13. Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands;

14. Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia;

15. Department of Critical Care Medicine, Albert Einstein Israelite Hospital, São Paulo, Brazil;

16. Department of Intensive Care, Austin Hospital, Melbourne, Australia;

17. Department of Surgical Sciences and Integrated Diagnostics, San Martino Policlinico Hospital, Scientific Institute for Research, Hospitalization and Healthcare for Oncology and Neurosciences, Genoa, Italy;

18. Mahidol – Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok, Thailand; and

19. Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom

Funder

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

Publisher

American Thoracic Society

Subject

Critical Care and Intensive Care Medicine,Pulmonary and Respiratory Medicine

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