MECHANICAL PROPERTIES OF POLYMER COATINGSCONTAINING HAP AND ACTIVE SUBSTANCE ON A METALSUBSTRATEWASNOCI

Author:

Goldsztajn Karolina1ORCID,Lisoń-Kubica Julia2ORCID,Jaworska Joanna3ORCID,Jelonek Katarzyna3ORCID,Kajzer Wojciech1ORCID,Szewczenko Janusz1ORCID

Affiliation:

1. The Silesian University of Technology, Faculty of Biomedical Engineering, Department of Biomaterials and Biomedical Engineering

2. The Silesian University of Technology, Faculty of Biomedical Engineering, Department of Biomaterials and Medical Devices Engineering

3. Centre of Polymer and Carbon Materials, Polish Academy of Sciences

Abstract

Titanium alloys are currently widely used in implantation, especially in orthopaedics. However, undesirablereactions caused by aluminium and vanadium ions released from the surface of the most commonly used alloys,Ti6Al4V and Ti6Al7Nb, result in the need to modify the surface of the material to improve biocompatibility.Among the available modification methods, one can mention the application of biodegradable polymercoatings, which, apart from improving biocompatibility by limiting the penetration of alloying element ionsinto the tissue environment, can also be a matrix for the release of mineral (HAp) and active substances. Thepaper attempts to determine the mechanical properties of PLGA polymer coatings containing nanoparticlehydroxyapatite and an active substance (dexamethasone) applied with the ultrasonic spray coating methodon a Ti6Al7Nb alloy substrate. The scope of the research included: surface topography testing using an opticalprofilometer, coating adhesion testing to the substrate using the scratch test method and tribological testing(Pin-On-Disc method).

Publisher

Index Copernicus

Subject

General Medicine

Reference16 articles.

1. GBD 2019 Fracture Collaborators: Global, regional, and national burden of bone fractures in 204countries and territories, 19902019: a systematic analysis from the Global Burden of Disease Study2019, The Lancet, vol. 2, 2021, pp. 580592.

2. Wang M.: Surface Modification of Metallic Biomaterials for Orthopaedic Application, MaterialsScience Forum, 2009, pp. 285231.

3. Liu X., Chu P.K., Ding C: Surface modifcation of titanium, titanium alloys, and related materials forbiomedical application, Mater. Sci. Eng. R, vol. 47, 2004, pp. 49121.

4. Kiel-Jamrozik M., Szewczenko J., Basiaga M., Nowiska K.: Technological capabilities of surfacelayers formation on implant made of Ti-6Al-4V ELI alloy, Acta of Bioengineering and Biomechanics,vol. 17, 2015, pp. 3137.

5. Brinks J., van Dijk E.H.C., Habeeb M., Nikolaou A., Tsonaka R., Peters H.A.B., Sips H.C.M., van deMerbel A.F., de Jong E.K., Notenboom R.G.E., Kielbasa S.M., van der Maarel S.M., Quax P.H.A.,Meijer O.C., Boon C.J.F.: The Effect of Corticosteroids on Human Choroidal Endothelial Cells: A Modelto Study Central Serous Chorioretinopathy, Invest Ophthalmol Vis Sci, vol. 59, 2018, pp. 56825692.

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3