MECHANICAL PROPERTIES OF POLYMER COATINGSCONTAINING HAP AND ACTIVE SUBSTANCE ON A METALSUBSTRATEWASNOCI
Author:
Goldsztajn Karolina1ORCID, Lisoń-Kubica Julia2ORCID, Jaworska Joanna3ORCID, Jelonek Katarzyna3ORCID, Kajzer Wojciech1ORCID, Szewczenko Janusz1ORCID
Affiliation:
1. The Silesian University of Technology, Faculty of Biomedical Engineering, Department of Biomaterials and Biomedical Engineering 2. The Silesian University of Technology, Faculty of Biomedical Engineering, Department of Biomaterials and Medical Devices Engineering 3. Centre of Polymer and Carbon Materials, Polish Academy of Sciences
Abstract
Titanium alloys are currently widely used in implantation, especially in orthopaedics. However, undesirablereactions caused by aluminium and vanadium ions released from the surface of the most commonly used alloys,Ti6Al4V and Ti6Al7Nb, result in the need to modify the surface of the material to improve biocompatibility.Among the available modification methods, one can mention the application of biodegradable polymercoatings, which, apart from improving biocompatibility by limiting the penetration of alloying element ionsinto the tissue environment, can also be a matrix for the release of mineral (HAp) and active substances. Thepaper attempts to determine the mechanical properties of PLGA polymer coatings containing nanoparticlehydroxyapatite and an active substance (dexamethasone) applied with the ultrasonic spray coating methodon a Ti6Al7Nb alloy substrate. The scope of the research included: surface topography testing using an opticalprofilometer, coating adhesion testing to the substrate using the scratch test method and tribological testing(Pin-On-Disc method).
Publisher
Index Copernicus
Reference16 articles.
1. GBD 2019 Fracture Collaborators: Global, regional, and national burden of bone fractures in 204countries and territories, 19902019: a systematic analysis from the Global Burden of Disease Study2019, The Lancet, vol. 2, 2021, pp. 580592. 2. Wang M.: Surface Modification of Metallic Biomaterials for Orthopaedic Application, MaterialsScience Forum, 2009, pp. 285231. 3. Liu X., Chu P.K., Ding C: Surface modifcation of titanium, titanium alloys, and related materials forbiomedical application, Mater. Sci. Eng. R, vol. 47, 2004, pp. 49121. 4. Kiel-Jamrozik M., Szewczenko J., Basiaga M., Nowiska K.: Technological capabilities of surfacelayers formation on implant made of Ti-6Al-4V ELI alloy, Acta of Bioengineering and Biomechanics,vol. 17, 2015, pp. 3137. 5. Brinks J., van Dijk E.H.C., Habeeb M., Nikolaou A., Tsonaka R., Peters H.A.B., Sips H.C.M., van deMerbel A.F., de Jong E.K., Notenboom R.G.E., Kielbasa S.M., van der Maarel S.M., Quax P.H.A.,Meijer O.C., Boon C.J.F.: The Effect of Corticosteroids on Human Choroidal Endothelial Cells: A Modelto Study Central Serous Chorioretinopathy, Invest Ophthalmol Vis Sci, vol. 59, 2018, pp. 56825692.
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