Diabetes association of polyps and colon cancer

Abstract

Aim The aim of the study was to retrospectively assess the relationship between the occurrence of polyps and colon cancer in patients with type 2 diabetes. Methods In 2014-2015, 976 colonoscopy was performed in patients. We compared the number of polyps with high-grade dysplasia and colorectal cancers in patients with and without diabetes. In addition, in the diabetic group, we documented the relationship between HbA1C and the occurrence of polyps high-grade dysplasia, and colon cancer. The data were statistically analyzed. Result 1) Patients with diabetes have a higher frequency of polyps with high-grade dysplasia/ carcinoma - (32/91 (35.16%) in comparison to patients without diabetes 136/885 (15.37%), p <0.001. 2) Patients with diabetes have a higher frequency of polyps with cancer - (9/91 (9.89%) as compared to patients without diabetes in patients 18/885 (2.03%), p <0.001. 3) Colorectal cancer occurred significantly more often in uncontrolled diabetes (p = 0.022) Conclusion The conducted study shows a significant association between type 2 diabetes and the incidence of colorectal adenomas. These findings may lead to the conclusion that diabetic patients are at a higher risk of developing colorectal cancer thus requiring more need for a controlled colonoscopy. Therefore it may be worth to consider a scheme for screening patients in the group mentioned above by performing colonoscopy.