Impact of bariatric procedures on carbohydrates and lipids metabolism in obese patients

Abstract

The aim of this study was to compare the efficacy of two laparoscopic bariatric procedures, i.e. Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (LSG) in terms of body mass reduction and improvement in carbohydrate and lipid metabolism. Material and methods: The study group consisted of patients subjected to RYGB (Group I) and LSG (Group II) procedures. Body mass and fasting concentrations of glucose, insulin, glycated haemoglobin, total cholesterol, HDL, LDL and triglycerides were evaluated on the day preceding the surgery and 1, 3 and 6 months thereafter. BMI, HOMA-IR and HOMA-B were calculated as well. Results: The reduction of BMI, glucose, insulin, glycated haemoglobin, triglycerides levels as well as the HOMA-IR, and HOMA-B indices and increase of HDL were observed in both groups 6 months after the surgery. No reduction of both total cholesterol and LDL concentrations was obtained in both groups. The differences of the studied parameters in both groups were not statistically significant. Conclusions: RYGB and LSG are equally effective in terms of body mass reduction, improvement of carbohydrates and lipid metabolism assessed 6 months after the surgery.