Surgical Treatment Outcomes in Metastatic Tumours Located at the Craniocervical Junction

Abstract

Background. Cancer metastases to the upper section of the cervical spine are found in a low percentage of patients. Their conservative treatment consists in radio- and chemotherapy as well as immobilisation in an orthopaedic collar. Surgery is the treatment of choice in patients with lesions causing spinal instability or compressing neural structures. The aim of this study was to assess the outcomes of surgical treatment conducted in patients with metastases located in the upper section of the cervical spine. Material and methods. The study analysed the medical records of 20 patients who underwent surgical treatment at the Department of Oncological Orthopaedics in Brzozów in 2015-2016. The majority of the patients were female (75%). The mean age of the male patients was 58 years and that of the female patients was 68 years. The most common complaints were pain (90%) and neurological deficits (50%; mainly Frankel Grade C). The most common primary tumour was breast cancer (35%). 58% of the patients had slow-growing tumours according to the Tomita system. Surgical procedures lasted a mean of 117 minutes and involved fixation of a mean of 7.5 levels. The treatment reduced the patients’ VAS score for pain by 3.89 points, improved function (Karnofsky scale) by 18 points and produced neurological improvement in 66% of the patients. The overall 2.5-year survival rate was 35%. The mean hospital stay lasted 14.5 days. One patient died on the 8th post-operative day due to cardiovascular complications. There was one case of delayed wound healing due to a haema­toma. No mechanical damage to the implants, infections, or cerebrospinal fluid leaks were found. Conclusions. 1. Metastases located in the upper cervical spine are rare and cause significant technical difficulties. 2. Fixation with lateral mass screws and plates fixed with screws to the occipital bone is a safe and effective method. 3. Surgical treatment allows for restoring spinal stability, reducing pain, and improving the patients’ quality of life.