Drugs containing extracts from Ruscus in chronic venal disease therapy – what's new we know about their effects?

Abstract

Pharmacotherapy of venous insufficiency is based on the use of drugs which, through their mechanism of action, contribute to the complex pathomechanism of this disease. One of the drugs used in the treatment of CVD are extracts of Ruscus. Numerous studies have demonstrated a multidirectional mechanism of action involving the effect of the drug on the adrenergic and cholinergic systems and the intracellular calcium metabolism. All these mechanisms are responsible for the multidirectional mechanism of action of the drug.