Affiliation:
1. Izhevsk state medical Academy
2. Republican Clinical Diagnostic Center, Department of Rheumatology
Abstract
Sarcoidosis is an inflammatory disease characterized by the formation of non-caseating granulomas in various organs and tissues. The clinical signs of sarcoidosis are determined by the number of affected organs, the degree of their structural and functional impairment, and the severity of inflammatory symptoms. The article presents a clinical observation of one of the forms of sarcoidosis — Lofgren’s syndrome, which is characterized by a triad of intrathoracic lymphadenopathy, acute arthritis and erythema nodosum. The diagnosis was confirmed histologically. Under the prescribed treatment, signs of acute inflammation reversed and the patient’s state improved. The authors emphasize that they do not recommend widespread use of systemic glucocorticosteroids in patients with this disease, since their use may be associated with a relapsing course.
Reference6 articles.
1. Terpigorev S.A., El' Zein B.A., Vereshchagina V.M. i dr. Sarkoidoz i problemy ego klassifikatsii. Vestnik Rossiiskoi akademii meditsinskikh nauk. 2012; 67(5): 30-37; Terpigorev S.A., El-Zein B.A., Vereshagina V.M., Paleev N.R. et al. Sarcoidosis: problems in classification. Annals of the Russian academy of medical sciences. 2012; 67(5): 30-37 [In Russian];
2. Ungprasert P., Crowson C.S., Matteson E.L. Clinical Characteristics of Sarcoid Arthropathy: A Population-Based Study. Arthritis Care and Research. 2016; 5: 695-699;
3. Abril A., Cohen M.D. Rheumatologic manifestations of sarcoidosis. Current opinion in rheumatology. 2004; 1: 51-55;
4. Visser H., Vos K., Zanelli E., et al. Sarcoid arthritis: clinical characteristics, diagnostic aspects, and risk factors. Annals of the Rheumatic Diseases. 2002; 6: 499-504;
5. Vizel' I.Yu., Vizel' A.A. Osobennosti sostoyaniya bol'nykh sarkoidozom s sindromom Lefgrena pri ikh vyyavlenii i pri razlichnykh variantakh lecheniya i nablyudeniya. Prakticheskaya pul'monologiya. 2016; 1: 44-49; Vizel I.Yu., Vizel A.A. Features of the condition of patients with sarcoidosis with Lefgren’s syndrome when they are detected and with various treatment and observation options. Practical pulmonology 2016; 1: 44-49;
Cited by
2 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献