Synergistic effects of Piper longum mediated MgO nanoparticles for bacterial and fungal inhibition

Abstract

Abstract A simple, cost-efficient green synthesis has been reported in the present study to synthesise and study the antimicrobial activity of the Piper longum assisted magnesium oxide nanoparticles (MgO-NPs). The MgO nanoparticles were prepared by co-precipitation method and characterised by x-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), and ultraviolet visible absorption spectroscopy (UV-vis), energy dispersive x-ray (EDX) and transmission electron microscopy (TEM) analysis. The XRD study represents the FCC lattice of MgO- NPs. The adsorption of polyphenols and proteins in the P.longum extract on the surface of the prepared MgO-NPs was identified by FTIR. HR-TEM shows spherical particles with average size 22.67 nm due to the sufficient amount of capping. The energy band gap for MgO-NPs was found to be 5.1 eV. The optical studies indicate the quantum confinement effect of magnesium oxide NPs prepared with increasing concentration of Piper longum. The results indicated that small particle sized MgO-NPs have improved antimicrobial activity towards Pseudomonas aeruginosa, Staphylococcus aureus and Aspergillus flavus. The functional activities of the Piper longum assisted magnesium oxide NPs were influenced largely by the particle size. The obtained results revealed that the green synthesised MgO-NPs demonstrated assuring biomedical potentials.