Author:
Zhang Jie,Qiang Genrong,Shen Tianhua,Pan Lifang,Xu Lijuan,Song Qingbao
Abstract
Abstract
A series of heterocyclic compounds 3-acetyl-2,5-disubstituted-1,3,4-oxadiazolines (2a-2g) were prepared with hydrazones and acetic anhydride. The products were characterized by 1H-NMR, 13CNMR, IR and elemental analysis. Furthermore, these compounds were tested for their bioactivities of anti-Staphylococcus aureus, HIV-1 RT (Human Immunodeficiency Virus Type 1 Reverse Transcriptase) and proliferative. However, there were no compounds showed promising activities with S. aureus, HIV-1 RT, HT-29 cells and HT-1080 cells.
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