Hypolipidemic Effects of Polysaccharides from Fermented Seaweed

Abstract

Abstract To study the hypolipidemic effect of a fermented seaweed polysaccharide on experimental hyperlipidemic mice for Conducted a series of work. Algal polysaccharides can alleviate hyperlipidemia and decrease risks of atherosclerosis and cardiovascular diseases. This study aimed to investigate effects of algal polysaccharides fermented by Yeast and Lactobacillus plantarum on hematic fat level of mice fed with high fat diet. Forty mice were randomly assigned to four groups: normal control group (NC), high-fat control group (HFC), high concentration of seaweed polysaccharide (HSP), low concentration of seaweed polysaccharide (LSP), respectively. The NC group was fed with the basic diet, while the other groups were fed with high-fat diet. After the experimenta period (4W), mice were sacrificed by decapitation. Results demonstrated that fermented algal polysaccharides could regulate lipid levels, the increase in HDL-c and decrease in TG, TC and LDL-c. In conclusion, algal polysaccharides fermented by Yeast and Lactobacillus plantarum may has effect of hypolipidemic.