Nanocomposite Gold Nanoparticles and Hyaluronic acid synthesis using the atmospheric air jet plasma

Abstract

Abstract The atmospheric cold plasma has been used in the synthesis of gold nanoparticles using different molar concentration from Aqueous gold tetrachloride salts HAuCl4.4H2O mixed with Hyaluronic acid (HA) using a low-cost and simple method in order to create a cold plasma at exposure time of 6 min. The effect of mixing with different concentrations ratio of gold salts with 1mM of hyaluronic acid with ratio Gold salt:HA (10:1) were studied with the same exposure time which stated above to determine the best concentration for nanoparticles of gold. X-ray diffraction (XRD), UV-Visible spectra were used to characterize the nanoparticles. The synthesis of AuNPs indicated to surface Plasmon resonance (SPR) at 540, 544,and 550 nm for samples that prepared. The strong intense peaks that showed in the XRD patterns for all prepared samples is indicating to the face centered cubic structure and nature of crystalline of nanoparticles. The average size of crystallite were from 20 to 40 nm for the AuNPs, and the FESEM showed the AuNPs morphology. and the synthesize of AuNPs were showed by observations are have spherical shape and have diameters sizes from 16 to 38 nm. The outcome of the study revealed that the atmospheric air cold plasma is a promising technique to be used in production of the nanoparticle’s materials for the medical application.