Cyclic Voltammetric Studies of Micro and Nano Paracetamol Using Glassy Carbon Electrode Modified with Multi-Walled Carbon Nanotube and Graphene

Abstract

Abstract The glassy carbon electrode (GCE) was modified with multiwalled carbon nanotube (MWCNT) and graphene (MWCNT/GCE), (graphene/GCE) to study the electrochemical behaviour of paracetamol using cyclic voltammetric technique at different paracetamol particles size (186μm, 4-9μm, 45nm) in a 10 ml solution of (1M) KCl and (0.1mM) paracetamol at scan rate (0.1 V/s). The results of cyclic voltammogram showed the anodic current peaks of paracetamol increases with decrease particle size. Also, the solubility is enhancement with decreasing particle size. MWCNT/GCE is a good biosensor with high electrochemical sensitivity for paracetamol than graphene/GCE.