Development of Voltage Amplifier Electronic Reader for Multiplex Detection of Two Electrode Electrical Biosensors

Abstract

Abstract Amperometric electrical biosensors have small current variations at nano to micro range. There are limited number of electrical based two electrode electronic readers for biosensors are commercial available because of the amplification and noise issues at nano to micro ampere current range. The electronic reader focused on design a voltage amplifier circuit to capture and amplify three different range of current as nano, micro and mili ampere and convert it to detectable voltage range as an output voltage signal. Current input as nano, micro and mili current were flown through 10 K Ω, 10 Ω and 10 m Ω resistors, respectively to convert different current inputs to the similar range in micro voltage. Then, MAX 4238 op-amp IC was used to amplify micro voltage to mili voltage. Arduino Uno circuit was act as the process and control circuit to read the output voltage from the amplifier circuit. Arduino Uno circuit will convert analog signal to digital signal and then the output voltage value is display in the LCD screen. The Proteus 8 Pro software was used to design, simulate and calibrate the amplifier circuit and Arduino Uno circuit. While, Arduino software was used to create a programming code and to upload in Arduino Uno circuit. Start your abstract here.