Synthesis of blue fluorescent carbon dotsfor sensitive and selective detection of glucose in biological samples

Abstract

Abstract This Article describes a technique for the preparation of blue fluorescent carbon dots (CDs) showing fluorescence emission at 450nm. CDs were prepared using ultra-sonication technique using citric acid and glycerol as precursors. Since glucose quenches the fluorescence of CDs, depending upon this fact, a fluorescent sensor for glucose determination has been established. Under optimized conditions, linear response in therange of 0.1-100µM was obtained for glucose concentration. Limit of detection is found to be 0.08µM. This method was promisingly used for the glucose determination in serum albumin samples and urine samples from different human beings.