Central Composite Design for Solvent Extraction of Oil from Neem (Azadirachta indica) seed

Author:

Ojewumi M. E.,Ehinmowo A.B.,Ekanem G.P.,Nsionu J.U.,Bolujo E.O.

Abstract

Abstract Optimization of neem oil extraction using Central Composite Design (CCD) was evaluated in this research. The effects of two factors: sample weight and extraction duration on the response which is neem oil volume extracted, were investigated. The CCD employed resulted in 13 experimental runs. Extraction was carried out in a 250 ml Soxhlet extractor. Hexane was used as solvent with thermostated heating mantle at temperature 60°C. Results obtained shows the optimized values of 54.69% of neem oil was obtained with 25 g weight of sample with extraction time of 12hours. The r2 and r2adj values were close to 1 which indicates that the regression model was a good one.

Publisher

IOP Publishing

Subject

General Medicine

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