Effect of porogen agent on microstructure of CaP granules using the gelation of alginate droplet formation

Abstract

Abstract CaP granules are used for open defect of bone. The important feature in the physical structure of a synthetic ceramic is its porosity. Pore structure is great importance for osteoconduction. The main objective of this study is to investigate the effect of adding carbon black as porogen agent on microstructure of CaP granules of droplet CaP. According to that, certain carbon black (325 mesh) has added into composition of microspheres CaP-alginate gelation with ratio CaP:Carbon black was 0.5, 1, and 1,5 weight ratios respectively. Scanning Electron Microscope (SEM) was used to investigate microstructure of droplet and shown that Irregular shape grain. Internal microstructure appears more open for samples produced without a presence of alginate after sintering process and confirmed by XRD pattern for whole samples. The porosity and pore size increased by increasing CB. On the other hand, no significant change on surface roughness and no transformation phase caused by adding CB. So that, it can be concluded that CB can serve as a porogen agent.