On The Application of Diffusion Magnetic Resonance Imaging for Study of Agarose

Abstract

Abstract The precise and accurate measurements of material properties are needed in biomaterial and tissue engineering study to better describe the properties of material and ensure the product quality Diffusion Magnetic Resonance Imaging (MRI) is used in biomaterial study as a biomarker for composition and structure of biomaterial and a tool to observe mechanical properties of materials. The previous study predicted the mechanical properties of polyvinyl alcohol (PVA)-based material for biomedical phantom using diffusion MRI. The measurement was performed based on water diffusion inside gel and the method only worked for a certain concentration of PVA. In this study, Diffusion MRI was used to observe water diffusion of agarose as a potential hydrogel material for phantom development and tissue-mimicking materials.