Effect of hydrothermal time and acid-washing on the antibacterial activity of Sodium titanate nanotubes

Abstract

Abstract Bacterial resistance to antibiotics has been a major concern globally. In this work, sodium and hydrogen titanate nanotubes were successfully synthesised using a facile hydrothermal technique. The prepared samples were characterized by XRD, FTIR, HRTEM surface area analyser, hydrodynamic size analyser and zeta potential. Minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC) measurements besides agar well diffusion method showed good antimicrobial activity of both nanotubes. The antimicrobial activity of sodium titanate nanotubes prepared at 6 and 23 hr., and their hydrogen exchanged forms; (HTNT) and (HTNS) explored good antimicrobial activity against both Gram positive and Gram negative bacteria besides their antifungal activity which reflects their importance in treatment of bacterial infections causing serious diseases in both animal and human.