Pathological Study of Experimental Glyphosate Toxicity in Mosquito Fish Gambusia affinis

Abstract

Abstract The present study deals with the effect of herbicide glyphosate on mosquito fish Gambusia affinis. Fish were exposed to different concentrations of the mentioned pesticide, behavioral and histological effects of various concentrations of glyphosate on mosquito fish Gambusia affinis in the acute exposure (96) hours were investigated.There were behavioral changes on the exposed fishes represented by nervous symptoms, loss of equilibrium, increas in respiration rate, opening of mouth and histological changes were determined in gills after acute exposed such as hyperplasia, hemorrhage, aneurysms, separation of epithelial layer, clubbing with sickle lamellae, hypertrophy, destroyed and fusion of secondary lamellae.The liver tissues were showed that hypertrophy of nucleus and necrosis and degeneration and swelling of cells, increasing of size and bleeding and congestion of blood vessels and bilirubin pigment diffusing around bile duct, in kidney tissues there were necrosis and degeneration of epithelial cells of tubules, increasing of size of Bowman᾿ s capsule, congestion and atrophy and disappear of glomerulus, separation of tubules, increasing of size and congestion of blood vessels, bleeding between tubules and bilirubin pigment diffusing around blood vessels.