Some immunological parameters in abuse substance addicted

Abstract

Abstract Drugs are chemicals which cause either physical or mental changes in body functioning. These chemicals may be natural, such as cocaine, semi-synthetic, such as heroin and ecstasy, or totally synthetic, such as methadone The study was occurred between February and August of 2018 on drug users in Najaf government. 50 of whom were abusers, twenty as healthy control group at age 17-25 years. Multi drug rapid test was use to qualitative test for abuse substances. The results appeared a high percentage of alcohol abusers (18%), other types 16% synthetic Marijuana (K2), Benzodiazapines – alcohol 13%, Amphetamine (AMP )12%, AMP + Methylendi oxymeth amphotamine (MDMA) + K was11%, (AMP + BZO + Marijuna THC), 9% K2 + AMP (7% K2 + BZO + THC), 5% THC), respectively. Some immunological parameters was studied. the results found IgG concentration was significantly higher at 912.49 compare with control 882.74, as well as alcohol 11475.35, BZO + alcohol 925.33, AMP + MDMA + K (1480,83), AMP + BZO + THC (1616.6), Showed a higher concentration of control, but some abusers had a lower concentration than control, (332.53) Amp, K2, (576. 66) THC, (476. 6) K2 + BZO + THC 690.766 pg/ml. IgM concentration was high 177.27 in addicted compare with control 61.3, and high in all drugs. Results showed that Interleukin10 concentration was 104.04pg/ml found a high contrast with control 39.19 and all abusers had concentrations higher than control.