Ultra-fast laser modification of poly-lactic acid (PLA) -towards enhanced biocompatibility

Abstract

Abstract In this study, the interaction was investigated of femtosecond laser radiation (pulse duration τ = 130 fs, wavelength λ = 800 nm) with poly-lactic acid (PLA) 2D scaffolds. Two sets of laser fluences (F) and scanning speed (V) values were applied to PLA matrices -F = 1.66 J/cm2, V = 3.8 mm/s, and F = 0.83 J/cm2, V = 3.8 mm/s. The PLA samples thickness, roughness, and water contact angle (WCA) were characterized before and after the laser structuring. The fs-induced micro structures were investigated by SEM, EDX, and FTIR analyses. Preliminary cell fibroblast studies were performed. The results obtained clearly show that a precise laser surface structuring could orient the cells matrix ingrowth and thus make PLA bone tissue engineering interbody future application more successful and adaptable to the personal needs of the recipients.