The effect of extract guava, bitter melon, broccoli, and shallots on liver damage due to indoor pollutant exposure

Abstract

Abstract Air freshener is a chemical-based product commonly used to freshen the air in the room. However, it usually has a variety of harmful compounds, and if it enters the body it can trigger the formation of free radicals, which in turn can cause cell and tissue damage in vital organs such as liver. One way that can be used to treat cell damage due to free radicals is by consuming foods that contain antioxidants. In this study, mice were used to determine the effectiveness of the antioxidant extracts of guava, bitter melon, broccoli, and shallots. Types of free radicals and levels of liver cells damage of mice due to free radicals were analyzed using quantitative atomic spectroscopy and levels assay of malondialdehyde (MDA). The results showed that the effect of the antioxidants mentioned above could reduce the number of free radicals and cell damage that occurred in the liver of mice exposed to air freshener, and the optimal dose of antioxidants was obtained at 69.5 mg per 20 grams of mice.