Synthesis and DNA binding study of Co (II) and V(IV) complexes with O, N, O tridentate 3-methoxysalicylaldehyde-semicarbazide based ligand

Abstract

Abstract Cobalt and vanadium complexes with (E)-2-(2-hydroxy-3-methoxybenzylidene)hydrazine-1-carboxamide were synthesized. The ligand was structurally characterized by FTIR, 1HNMR and 13CNMR spectroscopy. The interaction activity of ligand and complexes was investigated with DNA by spectroscopical and physical methods. The results showed an intercalative binding between the synthesized compounds and DNA.