Synthesis of steroid bearing heterocyclic derivatives and biological activity. Review 2014-2020

Abstract

Abstract Steroidal building blocks have drawn research groups attention in many branches of science and technology, such as pharmacological and medical fields, supramolecular chemistry and compounds in nanotechnology, So the recent years have witnessed a wide focus of research directed towards preparing heterocyclic derivatives fused with steroid molecules as a result of the great biological activity these compounds, This review described an outline of the literature reports (2014-2020) of synthesis heterocyclic compounds for steroid molecules fused at rings-A or B or D of steroid skeleton or annealed, Also the review included the biological activity of steroid hetero cyclic as anti breast cancer, anti prostate cancer, antioxidant and antimicrobial.