Analysis of infrared spectra of blood serum of patients with multiple myeloma
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Published:2021-11-01
Issue:1
Volume:2103
Page:012052
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ISSN:1742-6588
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Container-title:Journal of Physics: Conference Series
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language:
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Short-container-title:J. Phys.: Conf. Ser.
Author:
Chernyshev D A,Mikhailets E S,Telnaya E A,Plotnikova L V,Garifullin A D,Kuvshinov A Y,Voloshin S V,Polyanichko A M
Abstract
Abstract
Multiple myeloma (MM) is a serious disease that is difficult to diagnose especially at early stage. Infrared spectroscopy is a promising approach for diagnosing MM. The principal component analysis (PCA) allows us to reduce the dimension of the data and keep only the important variables. In this study, we apply principal components analysis to infrared (IR) spectra of blood serum from healthy donors and multiple myeloma patients. As a result of the analysis by PCA, it was possible to visualize the separation of patient’s and donor’s samples into two clusters. The result indicates that this method is potentially applicable for diagnosis of multiple myeloma.
Subject
General Physics and Astronomy
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