Design and Synthesis of Polyacrylamide Quaternary Ammonium Salt with Antibacterial Activity

Abstract

Abstract Propenamine quaternary ammonium salt (NNDBAB) containing unsaturated bonds was synthesized from propenamine and bromobutane by alkylation reaction. Using NNDBAB as a monomer, PNNDBAB was further self-polymerized by free radical polymerization to produce propenamine quaternary ammonium salt (PNNDBAB). The structure of NNDBAB was characterized by infrared spectroscopy and nuclear magnetic resonance spectroscopy. The antibacterial properties of PNNDBAB were characterized by an antibacterial zone test, minimum inhibitory concentration, and smear plate counting. The results showed that PNNDBAB had good bacteriostatic activity, the diameter of the bacteriostatic zone was 27 mm, the minimum bacteriostatic concentration was 0.5 mg/L, and the bacteriostatic rate of 1wt% was 71.0%. The bacteriostatic effect was significant. The antibacterial effect of PNNDBAB is long-lasting. When added to the emulsion, the antibacterial effect of PNNDBAB can be sustained within 15 days.