Study on self-assembly of novel hydrophilic silane containing PEG segments and its resistance to protein adsorption

Abstract

Abstract A new type of hydrophilic silane containing PEG (polyethylene glycol) segments was produced in this study. Membranes were produced through self-assembly. Hydrophilic silane was characterized by FTIR, 1H-NMR; The chemical composition and surface morphology of the self-assembled membrane surface were characterized by AFM, CA, SEM; The material’s resistance to protein adsorption was studied by UV-Vis and coomassie brilliant blue method [1]. The results showed that the novel hydrophilic silane containing PEG segments can be successfully assembled on silicon substrates; self-assembled membranes and blank silicon substrates in comparison, protein adsorption decreased from 274.8 μg/cm2 to 145.7 μg/cm2. This study has important reference significance for the preparation of anti-protein adsorption and bacterial adhension materials.