Using retrosynthesis to raise a possible feasible synthesis of pileotin A and B

Abstract

Abstract The purpose of this report was to raise a feasible synthesis of Pileotin A and B. To achieve this goal, retrosynthesis of Pileotin A and B was performed by breaking these molecules into small and available pieces and then all these pieces were sticked by feasible chemical reaction to raise possible synthesis strategies for Pileotin A and B. Since there was no previous relevant experiment about this synthesis strategies, the feasibility was only established by the studied reactivities and the mechanism of each function group and reaction. Therefore, modifications were probably necessary to promote the reaction rate and achieve green chemistry when this synthesis was performed in real lab.