Recent progress in electrochemical immunosensors for SARS-CoV-2 detection

Abstract

Abstract SARS-CoV-2 has been threatening the human’s health which caused numerous infections and deaths since its outbreak in 2020. Various techniques for its detection have been researched and published for early diagnosis of SARS-CoV-2 to reduce infections. Currently, most methods target on the RNA using the PCR. It is reliable to the laboratory and professional staffs, but is inconvenient and untouchable for citizens to do the rapid test these days. In this review, the recent progress of design for SARS-CoV-2 detection using the electrochemical immunosensors, a kind of biosensors, has been introduced. Unlike the other skills, it targets on the antigen of the virus and the diagnostic results can be obtained through the current or potential changes caused by the redox reaction of the immunocomplex. In addition, this review would focus on the selection of the bio-receptor, the assay format and the modification of the electrode. This paper will hopefully shed light on pathogen detection with electrochemical immunosensors.