Gallium and magnesium substituted hydroxyapatite/carbon nanofiber composite: Improved mechanical and bioactivity for biomedical implant applications

Abstract

Abstract The primary goal of this effort is to develop an appropriate bone replacement material that exhibits superior biological, mechanical, and antimicrobial properties for potential use in the orthopedics field. For this purpose, the present work focuses on the development of gallium (Ga) and magnesium (Mg) substituted hydroxyapatite (Ga,Mg-HAP)/carbon nanofiber (CNF) composite coating on Ti6Al4V alloy. A number of methods, including X-ray diffraction (XRD), scanning electron microscopy (SEM), and Fourier transform infrared spectroscopy (FTIR), were used to assess the mechanical, morphological, and structural characteristics of the Ga,Mg-HAP/CNF composite coated Ti6Al4V. Additionally, the composite’s antibacterial activity is evaluated against E. Coli and S. aureus. On various incubation days, the HOS MG63 cell’s viability on the composite coating was evaluated. The obtained result clearly shows that while the substitution of minerals would improve the biological features of the composite sample, the reinforcement of the CNF in Ga,Mg-HAP increases the mechanical strength of the composite. Therefore, the Ga,Mg-HAP/CNF composite coated Ti6Al4V will be a viable implant for applications involving biological implants.