Simulation study of biopolymer microspheres shape varying behavior

Abstract

Abstract Simulation and modeling are very strong tools to design and simulate engineering cases that can be difficult to ably experimentally. In microscale domains, simulation and modeling play a very strong role to maintain results for specific cases that are hard to explain in microfluidic devices experimentally. Microfluidic devices were developed for mixing, separation, drug delivery, and microspheres formation. Drug delivery and microfluidic devices and modeling have a tight relationship that can solve and discuss the behavior of microspheres under variable formation process conditions. The main goal of this research is to discover the microspheres formation behavior under different flow rates. Experimentally, starch microspheres were formed with a different shape ranging from oval to spherical shape. This difference in shape was the main goal to study in this paper. To understand the shape changing, a numerical simulation study has been introduced using (ANSYS workbench 16.1) program, to simulate and study the microspheres formation process and the effect of flow rate varying on microspheres formation.