Reconstruction of Depolarization Pattern in Myocardial Infarction Cases Using Two Cascaded Stages of Artificial Neural Networks

Abstract

Abstract Our paper introduces a new technique for diagnosis of various heart diseases without the need of highly experts to investigate the electrocardiogram (ECG). Using the same electrodes of the ECG machine, it will be able to transmit directly the electrical activity inside the heart to a moving picture. Our technique is based on artificial intelligence algorithm using artificial neural networks (ANN). Finding the trans-membrane potential (TMP) inside the heart from the body surface potential (BSP) is known as the inverse problem of ECG. To have a unique solution for the inverse problem the data used should be obtained from a forward model. A three dimensional (3-D) model of cellular activation whole heart embedded in torso is simulated and solved using COMSOL Multiphysics software. In our previous paper, one ANN succeeded in displaying the wave propagation on the surface of a normal heart. In this paper, we used a configuration of ANNs to display different cases of heart with myocardial infarction (MI). To check the system accuracy, eight MI cases with different sizes and locations in the heart are simulated in the forward model. This configuration proved to be highly accurate in displaying each MI case -size and location- presenting the infarction as an area with no electrical activity.