Roadmap for precision preclinical x-ray radiation studies

Author:

Verhaegen FrankORCID,Butterworth Karl TORCID,Chalmers Anthony JORCID,Coppes Rob PORCID,de Ruysscher Dirk,Dobiasch Sophie,Fenwick John DORCID,Granton Patrick V,Heijmans Stefan H JORCID,Hill Mark AORCID,Koumenis ConstantinosORCID,Lauber KirstenORCID,Marples BrianORCID,Parodi KatiaORCID,Persoon Lucas C G G,Staut NickORCID,Subiel AnnaORCID,Vaes Rianne D WORCID,van Hoof StefanORCID,Verginadis Ioannis LORCID,Wilkens Jan JORCID,Williams Kaye JORCID,Wilson George DORCID,Dubois Ludwig JORCID

Abstract

Abstract This Roadmap paper covers the field of precision preclinical x-ray radiation studies in animal models. It is mostly focused on models for cancer and normal tissue response to radiation, but also discusses other disease models. The recent technological evolution in imaging, irradiation, dosimetry and monitoring that have empowered these kinds of studies is discussed, and many developments in the near future are outlined. Finally, clinical translation and reverse translation are discussed.

Publisher

IOP Publishing

Subject

Radiology, Nuclear Medicine and imaging,Radiological and Ultrasound Technology

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