Abstract
Abstract
Objective. Improving the local uniformity of
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field for awake monkey brain magnetic resonance imaging (MRI) at ultra-high fields while facilitating convenient placement and fixation of MRI-compatible multimodal devices for neuroscience study, can eventually advance our understanding of the primate’s brain organization. Approach. A group of single-channel RF coils including conventional loop coils and loopole coils sharing the same size and shape were designed for comparison; their performance as the transmit coil was quantitatively evaluated through a series of numerical electromagnetic (EM) simulations, and further verified by using 7T MRI over a saline phantom and a monkey in vivo. Main results. Compared to conventional loop coils, the optimized loopole coil brought up to 23.5%
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uniformity improvement for monkey brain imaging in EM simulations, and this performance was further verified over monkey brain imaging at 7T in vivo. Importantly, we have systematically explored the underlying mechanism regarding the relationship between loopole coils’ current density distribution and
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uniformity, observing that it can be approximated as a sinusoidal curve. Significance. The proposed loopole coil design can improve the imaging quality in awake and behaving monkeys, thus benefiting advanced brain research at UHF.
Funder
National Natural Science Foundation of China
Fundamental Research Funds for the Central Universities
National Key Research and Development Program of China
Key-Area Research and Development Program of Guangdong Province
MOE Frontier Science Center for Brain Science & Brain-machine Integration at Zhejiang University
Subject
Radiology, Nuclear Medicine and imaging,Radiological and Ultrasound Technology
Cited by
2 articles.
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