Extracting actigraphy-based walking features with structured functional principal components

Abstract

Abstract Objective. We extract walking features from raw accelerometry data while accounting for varying cadence and commonality of features among subjects. Walking is the most performed type of physical activity. Thus, we explore if an individual’s physical health is related to these walking features. Approach. We use data collected using ActiGraph GT3X+ devices (sampling rate = 80 Hz) as part of the developmental epidemiologic cohort study, I = 48, age = 78.7 ± 5.7 years, 45.8% women. We apply structured functional principal component analysis (SFPCA) to extract features from walking signals on both, the subject-specific and the subject-spectrum-specific level of a fast-paced 400 m walk, an indicator of aerobic fitness in older adults. We also use the subject-specific level feature scores to study their associations with age and physical performance measures. Specifically, we transform the raw data into the frequency domain by applying local Fast Fourier Transform to obtain the walking spectra. SFPCA decomposes these spectra into easily interpretable walking features expressed as cadence and acceleration, which can be related to physical performance. Main results. We found that five subject-specific and 19 subject-spectrum-specific level features explained more than 85% of their respective level variation, thus significantly reducing the complexity of the data. Our results show that 54% of the total data variation arises at the subject-specific and 46% at the subject-spectrum-specific level. Moreover, we found that higher acceleration magnitude at the cadence was associated with younger age, lower BMI, faster average cadence and higher short physical performance battery scores. Lower acceleration magnitude at the cadence and higher acceleration magnitude at cadence multiples 2.5 and 3.5 are related to older age and higher blood pressure. Significance. SFPCA extracted subject-specific level empirical walking features which were meaningfully associated with several health indicators and younger age. Thus, an individual’s walking pattern could shed light on subclinical stages of somatic diseases.