Abstract
The variational principle of minimum free energy (MFEVP) has been widely used in research of soft matter statics. The MFEVP can be used not only to derive equilibrium equations (including both bulk equations and boundary conditions), but also to develop direct variational methods (such as Ritz method) to find approximate solutions to these equilibrium equations. We apply these variational methods to study long-range force transmission in nonlinear elastic biopolymer gels. It is shown that the slow decay of cell-induced displacements measured experimentally for fibroblast spheroids in three-dimensional fibrin gels can be well explained by variational approximations based on the three-chain model of biopolymer gels.
Subject
General Physics and Astronomy