Microwave emissions from the cold atmospheric helium plasma jet

Abstract

Abstract One of the recently observed effects of plasma in medical applications is the physical effect, suggesting that the electromagnetic (EM) emission of cold atmospheric plasmas can lead to cell membrane oscillations and sensitization to the chemical active ingredient of treatments such as cancer drugs. This is a new aspect that must be considered along with the plasma chemical effects for the future dose definition which is the most urgent research topic of plasma medicine. However, unlike the reactive oxygen and nitrogen species generated from plasma chemistry which is well-known as playing a key role in apoptosis cancer cells, the EM emission power spectrum and emission mechanism are still unquantified. This makes the uncertainty of the physical dosage of the therapy and thus impedes the further understanding and optimization of the plasma therapy. In this paper, we compute the 3D spatial distribution of the power density spectrum of EM emission from a cold atmospheric helium plasma jet. The simulations indicate that the plasma oscillations following the plasma streamer propagation are the main source of EM emission, while the emissions of the bulk current caused by net charge movements and the bremsstrahlung due to charge collisions are negligible. The results are also verified by a microwave power measurement using a heterodyne frequency sweep. These findings will thus fill out the last missing piece of the jigsaw before the plasma medicine community can define the dose in the future.