Author:
Ulyanov Sergey,Ulianova Onega,Saltykov Yury,Zaytsev Sergey,Ulyanov Alexander,Feodorova Valentina
Abstract
Abstract
A method for generating dynamic GB-speckles, formed during diffraction of focused Gaussian beams by moving virtual rough surfaces, obtained for two nucleotide sequences (the ompA genes of the Chlamydia psittaci GR9 and AMK-16 strains), is proposed. The statistical characteristics of the 1st- and 2nd-order statistics of GB-speckles, formed at a small number of scattering events, are studied. The difference in the manifestation of the Doppler effect in the dynamics of GB-speckles and for speckles, formed with a small number of scatterers, produced by light diffraction on physically-existing rough surfaces and in scattering micro-streams is revealed. The problems of interference of dynamic GB-speckles are considered. A new technique for detecting individual single nucleotide polymorphism in nucleotide sequences using the interference of dynamic GB-speckles is proposed.
Subject
Physics and Astronomy (miscellaneous),Instrumentation