Cerium-modified cryptomelane: an antibacterial activity against Pseudomonas aeruginosa

Abstract

Abstract K-OMS-2 (non-modified sample) and Ce-modified OMS-2 with different Ce-loading amounts were prepared by the refluxed method. The cryptomelane structure and elemental composition of synthesized samples were characterized with X-ray diffraction (XRD) and inductively coupled plasma mass spectrometry (ICP-MS), respectively. ICP-MS analysis revealed ~0.06 – 0.11 of K/Mn molar ratio and the Ce-loading amounts increased from 0 to —11.27 wt.% under increasing Ce-precursor concentration. Antibacterial activity against Pseudomonas aeruginosa was evaluated by the agar well diffusion method. The antibacterial ability against Pseudomonas aeruginosa was not recorded over K-OMS-2 (Ce0; 4.5 wt.% of K; 0 wt.% of Ce) and Ce3 (0.89 wt.% of K; 11.27 wt.% of Ce) samples while Ce2 sample (1.89 wt.% of K; 8.7 wt.% of Ce) showed a comparable antibacterial activity against Pseudomonas aeruginosa with ~12 mm of inhibition-zone diameter. This suggested the potentiality of using metal-modified cryptomelane in acceleration of antimicrobial ability.