Investigation of some Heavy Metals on Parameter of Blood and Oxidative Enzyme in CKD in Iraq-Al-Qadisiyah

Abstract

Abstract Sampling Blood collected for patients with renal failure of the dialysis group and the non-dialysis group for randomly for (40-60) age. And conduct tests CBC. The oxidation enzymes and some of the sample heavy metal (Ai, Cd, Cr, Pb and As) after digestion and measured in atomic spectrophotometer the result show They found a clear relationship between kidney failure and the effect of heavy metals. Where it affected the blood rate and the number of white blood cells and oxidation enzymes. Where were the values after conducting the tests (12.8 ± 0.45) (9.57 ± 0.62) (9.43 ± 0.47) respectively for control, hemodialysis and non-hemodialysis for Hp. Tests for WBCs (7.8 ± 0.32) (8.07 ± 0.75) (8.37 ± 0.50) respectively for control, hemodialysis and non-hemodialysis. The results of the current study showed in the age group (40_60) that there was a decrease in significant at (P< 0.05) in SOD, GSH and CAT for hemodialysis patients compared with control (0.336±0.035 Mg\dl), (0.4086±0.0041 Mg\dl) and (0.191±0.0051 Mg\dl) Consecutively, according to the table indicated (1-2) and That’s agreement with previous studies. The results of the current study showed in the age group (40_60) that there was a decrease in significant at (P< 0.05) in SOD, GSH and CAT for non-hemodialysis patients compared with control (0.748±0.071 Mg\dl), (0.838±0.019Mg\dl) and (0.335±0.0023 Mg\dl) Consecutively, according to the table indicated (1-2) and That’s agreement with previous studies