Relationship of SPP1 Promoter/Exon 5 gene polymorphism G>A/4187 in Some economic traits of Awassi sheep

Abstract

Abstract This study was conducted in Iraq, Karbala Province (15 kilometers south of Karbala city). at the livestock field site of the Barakat Abu al-Fadl al-Abbas Station for Sheep Farming, The purpose was to detect genetic variations in the Secreted Phosphoprotein1 (SPP1) gene in the promoter region of exon 5 in local Awassi sheep.The study involved a sample of 48 local Awassi sheep, consisting of 62 ewes and their offspring, from December 1, 2022, for seven months. Find the current study It was found that there is a single nucleotide polymorphism (SNP) in the Promoter region of exon 5 at position SNP/G>A: P/4187 in the SPP1 gene. The allele frequencies for G and A were 0.95 and 0.05, respectively. The results of the current study showed significant differences (P≤0.05) in heart girth among the lambs at birth and weaning depending on the SPP1 gene polymorphism, There have also been significant differences in daily milk production. This study concludes that there is a relationship between SNPS and certain economic qualities in local Awassi sheep that can be exploited in election and improvement programs.