The Effect of Fractionation Temperature Using Spinning Band Distillation on the Myristicin Content of Nutmeg Oil (Myristica fragrans)

Abstract

Abstract Myristicin is the main compound in nutmeg oil which has potential as an antioxidant, anti-inflammatory and antiproliferative. Miristicin can be obtained through the fractionation distillation process. Fractionated distillation generally requires very high columns to get better results. Spinning band distillation is one of the separation methods built on the principle of simple fractionated distillation with further improved processing efficiency. The purpose of this study was to examine the effect of fractionated temperature on the yield and content of myristicin. This experiment used a pressure of 15 mmHg, a reflux ratio of 5:1, and an equilibration time of 10 minutes. This study used 3 types of experiments with the treatment of differences in fractionated temperature ranges. Each experiment was divided into 4 fractions with different temperature ranges. The results showed that myristicin evaporates at temperatures above 230 °C (AET). The fractionation process under suitable operating conditions can result in high yields and concentrations of myristicin.