Author:
Struchkov N A,Nifontov K R,Alekseev R Z,Domotov V V
Abstract
Abstract
In modern conditions of Arctic development, the problem of hypothermia of humans and animals is becoming fundamental and applicable nature. Studying deep hypothermia effect and body recovery after it on experimental models of animals is relevant for world science. The article presents some aspects of the naturally low temperatures affect (-40° C and below) on the domestic pig’s body under the conditions of Yakutia (experimental research). To perform this task, we simulated the conditions of natural deep hypothermia, in which we studied the mechanisms of entering an anabiosis state and got the data of experimental animals’ brain and heart bioelectrical activity. The experiment was conducted according to the ethical standards of the European Convention for the Protection of Vertebrate Animals used for Experimental and Other Scientific Purposes No. 123 of 18 March 1986, Strasbourg, and the order of the Ministry of Health of the Russian Federation No. 199n of 01.04.2016 “on approval of the regulations of good laboratory practice”. Permission of the bioethical commission is available.
Reference7 articles.
1. Influence of the Far North low temperature on the animals’ body temperature in the experiment;Tomskiy;Yakut Medical Journal,2019
2. Thermophysical parameters of hypothermia;Burkov;Bahkortostan Medical Journal,2014
3. Thermophysical parameters of hypothermia;Burkov;Bahkortostan Medical Journal,2014
4. Statistical analysis of rats’ electroencephalograms in hypothermic conditions;Rabadanova;Herald of Dagestan State University,2011
5. Negative inotropic effects of epinephrine in the presence of increased β-adrenoceptor sensitivity during hypothermia in a rat model;Dietrichs;Cryobiology,2015