Impact of Coenzyme Q10 and Wheat Germ Oil on some Measures of Oxidation and Reproductive System Activity of Local Rabbits Buck Under Oxidative Stress Conditions

Abstract

Abstract Effects of different levels of 0.0 and 100 mg Coenzyme Q10/kg diet (CoQ10), 0.00 and 3 gm. WGO /kg (WGO) on a number of oxidation parameters, sex hormones, and histological structure of the testis in local rabbits buck were investigated under oxidative stress condition. A total 54 rabbits aged 4-5 months, randomly assigned to six treatments. Nine / treatment and three replicates per each. The results showed a significant decrease in GOT and GPT enzymes for T3 and T4 compared with the T1 and T2. With a significant decrease in cortisol levels. Treatments 3 and 4 showed a significant improvement in the GSH and MDA concentrations of normal and stressed rabbits compared with the control and the second. Treatment with H2O2 recorded decrease in hormones FSH, LH and testosterone compared to others. Whereas, treatments with CoQ10 and WGO, recorded an improvement in the concentration of FSH and LH hormones compared with others. The addition of Coenzyme Q10 and wheat germ oil improved histological structure of the testicle. We can conclude treatment with CoQ10 and WGO improved parameters of oxidation and the level of sex hormones, and histological structure of the testis.