Local oxidative responses of lacrimal fluid in horses in various types of keratopathies

Abstract

Abstract Equine keratopathies are commonly occurring ophthalmic condition affecting the equine industry. In this article, was using clinical material, a correlation was revealed between the occurrence of corneal diseases and increased tear`s antioxidant activity. The occurrence of keratopathies flows with a multidirectional alteration in antioxidants tears, what determines oxidative stress with inflammatory in cornea tissue - result of cell apoptosis and necrosis of the epithelium and endothelium barriers is triggered, the occurrence of corneal defects with marginal vascularization. Research result expands can help understand of pathogenesis keratopathies and can be applied in the future for approaches for prophylaxis and therapy of inflammation corneal diseases.