Data for Genomics in Healthcare: The Potential of Next-Generation Sequencing in Developing Precision Medicine

Author:

Antara Dafa Dwi,Lie Michael Yahezkiel,Darisza Muhammad,Kertapati Nicola,Valentino Ivan,Mahesworo Bharuno,Nurlaila Ika,Soeparno Haryono

Abstract

Abstract Recent advances in genomics on healthcare technology have opened the path towards more precise treatments by analysing patients’ genome using a high throughput DNA sequencing technology called Next Generation Sequencing (NGS). The information obtained is further used to determine a more effective treatment path for patients based on their genetic profiles. It can also be employed to predict the risk of patients developing certain diseases. Despite particular difficulties it might create in the first phase of settling the integrative frameworks down, a successful combination of NGS and Big Data technology would offer a huge improvement in terms of the effectiveness of treatments and medicine administration for the patients. This paper elucidates a general overview of how NGS-based DNA sequencing makes precision medicine possible and describes the use of Big Data for genomics in healthcare-wise.

Publisher

IOP Publishing

Subject

General Engineering

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