Kinetics of formation of reactive oxygen species by blood cells when exposed to ultra-low doses of ionizing radiation

Abstract

Abstract The article contains the results of hematological, immunological and chemiluminescent analysis of the functional activity of peripheral blood cells of five-year-old lactating cows from the central regions of the Krasnoyarsk Territory (Siberia, Russia) with different radiation status, at which the radiation doses of animals were 0.02, 0.17 and 0.21 mSv per year. It was established that small doses of radiation at 0.17 mSv per year and 0.21 mSv per year affect hematological parameters, increase the phagocytic activity of blood leukocytes and change the kinetics of the formation of active oxygen forms by blood cells, which is manifested as an increase in the time of formation of the maximum kinetics of spontaneous and activated secondary radicals, reduction of the total production of secondary radicals in the antigenic activation of blood cells in vitro and an increase in the volume of spontaneously produced primary radicals.