Utilisation of fish skin waste as a collagen wound dressing on burn injuries: a mini review

Abstract

Abstract The fish processing industries produce wastes such as skin, fish scales, stomach contents, and bones. Those organic wastes has not been widely used. The biggest content of fish processing industry is collagen. Fish skin has the highest collagen content (5%-30%). Collagen has been widely used in pharmaceuticals, cosmetics, and food. One of the benefits of collagen is as a wound dressing on burn injuries. Collagen as the most abundant fibrous protein in fish is the main constituent of the extracellular matrix (ECM). ECM is a dynamic substance between cells in a tissue and has the ability to improve the tissue functions. Burn injuries are one of the types of wounds that has a long healing phase, which requires intensive treatment. Severe burn injuries could make people who experience it have traumatic and paralysis that affects the entire organ system. Collagen wound dressing was expected to be able to engineer tissue and accelerate cell regeneration to replace or regenerate damaged tissues. This paper will describe the potency of fish skin waste, problems in healing burn injuries, collagen extraction, and collagen application as wound dressing.